New insights into the anticancer therapeutic potential of maytansine and its derivatives

New insights into the anticancer therapeutic potential of maytansine and its derivatives

Maytansine is a pharmacologically active 19-membered ansamacrolide derived from various medicinal plants and microorganisms. Among the most studied pharmacological activities of maytansine over the past few decades are anticancer and anti-bacterial effects. The anticancer mechanism of action is prim...

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Bibliographic Details
Main Authors: Sameen Zafar, Muhammad Armaghan, Khushbukhat Khan, Nazia Hassan, Javad Sharifi-Rad, Solomon Habtemariam, Marek Kieliszek, Monica Butnariu, Iulia-Cristina Bagiu, Radu Vasile Bagiu, William C. Cho
Format: Article
Language:English
Published: Elsevier 2023-09-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Maytansine
Derivatives
Antibody-drug conjugate
Cytotoxicity
Anticancer activity
Tubulin instability
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332223008296

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http://www.sciencedirect.com/science/article/pii/S0753332223008296

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