Synthesis and Biological Evaluation of New <i>N</i>-Acyl-α-amino Ketones and 1,3-Oxazoles Derivatives

Synthesis and Biological Evaluation of New <i>N</i>-Acyl-α-amino Ketones and 1,3-Oxazoles Derivatives

In order to develop novel bioactive substances with potent activities, some new valine-derived compounds incorporating a 4-(phenylsulfonyl)phenyl fragment, namely, acyclic precursors from <i>N</i>-acyl-α-amino acids and <i>N</i>-acyl-α-amino ketones classes, and heterocycles...

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Bibliographic Details
Main Authors: Theodora-Venera Apostol, Luminita Gabriela Marutescu, Constantin Draghici, Laura-Ileana Socea, Octavian Tudorel Olaru, George Mihai Nitulescu, Elena Mihaela Pahontu, Gabriel Saramet, Cristian Enache-Preoteasa, Stefania-Felicia Barbuceanu
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Molecules
Subjects:
<i>N</i>-acyl-α-amino acid
4-isopropyl-1,3-oxazol-5(4<i>H</i>)-one
<i>N</i>-acyl-α-amino ketone
4-isopropyl-1,3-oxazole
antimicrobial activity
antibiofilm agents
Online Access:https://www.mdpi.com/1420-3049/26/16/5019

Internet

https://www.mdpi.com/1420-3049/26/16/5019

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