Raman Spectroscopic Investigation of Osteoclastic Activity under the Influence of Bisphosphonate

The bone resorption inhibitor bisphosphonate (BP) is used to prevent fractures in patients with osteoporosis and bone metastases caused by cancer. However, BP induces apoptosis of osteoclasts and excessively suppresses bone turnover, so that side effects such as jawbone necrosis have become a proble...

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Bibliographic Details
Main Authors: Elia Marin, Tetsuya Adachi, Francesco Boschetto, Wenliang Zhu, Keiji Adachi, Narisato Kanamura, Toshiro Yamamoto, Giuseppe Pezzotti
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Applied Sciences
Subjects:
Online Access:https://www.mdpi.com/2076-3417/12/8/3757