Distinct actin–tropomyosin cofilament populations drive the functional diversification of cytoskeletal myosin motor complexes

Distinct actin–tropomyosin cofilament populations drive the functional diversification of cytoskeletal myosin motor complexes

Summary: The effects of N-terminal acetylation of the high molecular weight tropomyosin isoforms Tpm1.6 and Tpm2.1 and the low molecular weight isoforms Tpm1.12, Tpm3.1, and Tpm4.2 on the actin affinity and the thermal stability of actin-tropomyosin cofilaments are described. Furthermore, we show ho...

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Bibliographic Details
Main Authors: Theresia Reindl, Sven Giese, Johannes N. Greve, Patrick Y. Reinke, Igor Chizhov, Sharissa L. Latham, Daniel P. Mulvihill, Manuel H. Taft, Dietmar J. Manstein
Format: Article
Language:English
Published: Elsevier 2022-07-01
Series:iScience
Subjects:
Biological sciences
Biochemistry
Biomolecules
Protein
Biophysics
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004222007556

Internet

http://www.sciencedirect.com/science/article/pii/S2589004222007556

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