Heterogeneity of the Head and Neck Squamous Cell Carcinoma Immune Landscape and Its Impact on Immunotherapy

Heterogeneity of the Head and Neck Squamous Cell Carcinoma Immune Landscape and Its Impact on Immunotherapy

Head and neck squamous cell carcinomas (HNSCCs) are highly aggressive, multi-factorial tumors in the upper aerodigestive tract affecting more than half a million patients worldwide each year. Alcohol, tobacco, and human papillomavirus (HPV) infection are well known causative factors for HNSCCs. Curr...

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Bibliographic Details
Main Authors: Madison Canning, Gang Guo, Miao Yu, Calvin Myint, Michael W. Groves, James Kenneth Byrd, Yan Cui
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-04-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
head and neck squamous cell carcinomas
heterogeneity
immune landscape
immunosurveillance
immunosuppression
neoantigen
Online Access:https://www.frontiersin.org/article/10.3389/fcell.2019.00052/full

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https://www.frontiersin.org/article/10.3389/fcell.2019.00052/full

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