Gut microbiota-derived short-chain fatty acids promote prostate cancer progression via inducing cancer cell autophagy and M2 macrophage polarization

Gut microbiota-derived short-chain fatty acids promote prostate cancer progression via inducing cancer cell autophagy and M2 macrophage polarization

We have previously demonstrated abnormal gut microbial composition in castration-resistant prostate cancer (CRPC) patients, here we revealed the mechanism of gut microbiota-derived short-chain fatty acids (SCFAs) as a mediator linking CRPC microbiota dysbiosis and prostate cancer (PCa) progression....

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Bibliographic Details
Main Authors: Yufei Liu, Quan Zhou, Fangdie Ye, Chen Yang, Haowen Jiang
Format: Article
Language:English
Published: Elsevier 2023-09-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
CRPC
Gut microbiota dysbiosis
SCFAs
Autophagy
Macrophage polarization
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558623000520

Internet

http://www.sciencedirect.com/science/article/pii/S1476558623000520

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