Computational characterization of domain‐segregated 3D chromatin structure and segmented DNA methylation status in carcinogenesis

Computational characterization of domain‐segregated 3D chromatin structure and segmented DNA methylation status in carcinogenesis

The high‐order chromatin structure, together with DNA methylation and other epigenetic marks, plays a vital role in gene regulation and displays abnormal status in cancer cells. Theoretical analyses are expected to provide a more unified understanding of the multi‐omics data on the large variety of...

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Bibliographic Details
Main Authors: Yue Xue, Ying Yang, Hao Tian, Hui Quan, Sirui Liu, Ling Zhang, Lu Yang, Haichuan Zhu, Hong Wu, Yi Qin Gao
Format: Article
Language:English
Published: Wiley 2022-02-01
Series:Molecular Oncology
Subjects:
carcinogenesis
chromatin structure
DNA methylation
gene expression dysregulation
Online Access:https://doi.org/10.1002/1878-0261.13127

Internet

https://doi.org/10.1002/1878-0261.13127

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