PLSCR1 promotes apoptosis and clearance of retinal ganglion cells in glaucoma pathogenesis

PLSCR1 promotes apoptosis and clearance of retinal ganglion cells in glaucoma pathogenesis

Glaucoma is the leading cause of irreversible blindness worldwide. In the pathogenesis of glaucoma, activated microglia can lead to retinal ganglion cells (RGCs) apoptosis and death, however, the molecular mechanisms remain largely unknown. We demonstrate that phospholipid scramblase 1 (PLSCR1) is a...

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Bibliographic Details
Main Authors: Jingyi Luo, Qing Lian, Deliang Zhu, Minglei Zhao, Tingfang Mei, Bizhi Shang, Zeqiu Yang, Chujun Liu, Wenchang Xu, Lan Zhou, Keling Wu, Xinqi Liu, Yuhua Lai, Fuxiang Mao, Weihua Li, Chengguo Zuo, Kang Zhang, Mingkai Lin, Yehong Zhuo, Yizhi Liu, Lin Lu, Ling Zhao
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2023-07-01
Series:Genes and Diseases
Subjects:
Apoptosis
Glaucoma
Phagocytosis
PLSCR1
Retinal ganglion cells
Online Access:http://www.sciencedirect.com/science/article/pii/S2352304222001714

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http://www.sciencedirect.com/science/article/pii/S2352304222001714

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