Isobaric tags for relative and absolute quantitation-based quantitative proteomic analysis of X-linked inhibitor of apoptosis and H2AX in etoposide-induced renal cell carcinoma apoptosis

Abstract. Background:. X-linked inhibitor of apoptosis (XIAP) is a vital factor in the anti-apoptosis mechanism of tumors and is highly expressed in renal cell carcinoma (RCC). However, the mechanism through which XIAP regulates DNA damage repair is unknown. This study investigated the regulatory me...

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Bibliographic Details
Main Authors: Tian-Shu Liu, Chao Chen, Biao Zhou, Bo-Wen Xia, Zong-Ping Chen, Yong Yan, Xiu-Yuan Hao
Format: Article
Language:English
Published: Wolters Kluwer 2019-12-01
Series:Chinese Medical Journal
Online Access:http://journals.lww.com/10.1097/CM9.0000000000000553