Transcription factor competition facilitates self-sustained oscillations in single gene genetic circuits.

Genetic feedback loops can be used by cells to regulate internal processes or to keep track of time. It is often thought that, for a genetic circuit to display self-sustained oscillations, a degree of cooperativity is needed in the binding and unbinding of actor species. This cooperativity is usuall...

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Bibliographic Details
Main Authors: Jasper Landman, Sjoerd M Verduyn Lunel, Willem K Kegel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-09-01
Series:PLoS Computational Biology
Online Access:https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1011525&type=printable