Motor recruitment to the TIM23 channel’s lateral gate restricts polypeptide release into the inner membrane

Motor recruitment to the TIM23 channel’s lateral gate restricts polypeptide release into the inner membrane

The mitochondrial TIM23-complex facilitates anterograde precursor transport across the inner membrane into the matrix and lateral release of precursors into the membrane. Here authors show that the import motor J-protein Pam18 controls lateral protein release into the lipid bilayer.

Bibliographic Details
Main Authors: Alexander Benjamin Schendzielorz, Piotr Bragoszewski, Nataliia Naumenko, Ridhima Gomkale, Christian Schulz, Bernard Guiard, Agnieszka Chacinska, Peter Rehling
Format: Article
Language:English
Published: Nature Portfolio 2018-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-06492-8

Internet

https://doi.org/10.1038/s41467-018-06492-8

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