Dynamic change of fecal microbiota and metabolomics in a polymicrobial murine sepsis model

Dynamic change of fecal microbiota and metabolomics in a polymicrobial murine sepsis model

Aim Sepsis causes a systemic inflammatory reaction by destroying intestinal flora, which leads to a poor prognosis. In this study, we sought to clarify the characteristics of fecal flora and metabolites in a mouse model of sepsis by comprehensive metagenomic and metabolomic analysis. Methods We perf...

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Bibliographic Details
Main Authors: Arisa Muratsu, Mitsunori Ikeda, Kentaro Shimizu, Shoichiro Kameoka, Daisuke Motooka, Shota Nakamura, Hisatake Matsumoto, Hiroshi Ogura, Takeshi Shimazu
Format: Article
Language:English
Published: Wiley 2022-01-01
Series:Acute Medicine & Surgery
Subjects:
Metabolome
metagenome
microbiome
microbiota
sepsis
Online Access:https://doi.org/10.1002/ams2.770

Internet

https://doi.org/10.1002/ams2.770

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