Protein Stability Regulation in Osteosarcoma: The Ubiquitin-like Modifications and Glycosylation as Mediators of Tumor Growth and as Targets for Therapy

Protein Stability Regulation in Osteosarcoma: The Ubiquitin-like Modifications and Glycosylation as Mediators of Tumor Growth and as Targets for Therapy

The identification of new therapeutic targets and the development of innovative therapeutic approaches are the most important challenges for osteosarcoma treatment. In fact, despite being relatively rare, recurrence and metastatic potential, particularly to the lungs, make osteosarcoma a deadly form...

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Bibliographic Details
Main Authors: Jacopo Di Gregorio, Laura Di Giuseppe, Sara Terreri, Michela Rossi, Giulia Battafarano, Olivia Pagliarosi, Vincenzo Flati, Andrea Del Fattore
Format: Article
Language:English
Published: MDPI AG 2024-03-01
Series:Cells
Subjects:
cancer
osteosarcoma
post-translational modifications
ubiquitination
NEDDylation
SUMOylation
Online Access:https://www.mdpi.com/2073-4409/13/6/537

Internet

https://www.mdpi.com/2073-4409/13/6/537

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