Introducing Nafion for In Situ Desalting and Biofluid Profiling in Spray Mass Spectrometry

We introduce Nafion into the ambient ionization technique of spray mass spectrometry to serve for in situ desalting and direct analysis of biological fluids. Nafion was coated onto the surface of the triangular spray tip as the cation exchange material. Because the sulfonic group from the Nafion mem...

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Bibliographic Details
Main Authors: Xiaowei Song, Mohammad Mofidfar, Richard N. Zare
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-01-01
Series:Frontiers in Chemistry
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fchem.2021.807244/full