Specific inhibition of tumor cells by oncogenic EGFR specific silencing by RNA interference.

Specific inhibition of tumor cells by oncogenic EGFR specific silencing by RNA interference.

Anticancer agents that have minimal effects on normal cells and tissues are ideal cancer drugs. Here, we show specific inhibition of human cancer cells carrying oncogenic mutations in the epidermal growth factor receptor (EGFR) gene by means of oncogenic allele-specific RNA interference (RNAi), both...

Full description

Bibliographic Details
Main Authors: Masaki Takahashi, Tomoko Chiyo, Takashi Okada, Hirohiko Hohjoh
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3738543?pdf=render

Internet

http://europepmc.org/articles/PMC3738543?pdf=render

Similar Items