Alzheimer’s genes in microglia: a risk worth investigating

Abstract Despite expressing many key risk genes, the role of microglia in late-onset Alzheimer’s disease pathophysiology is somewhat ambiguous, with various phenotypes reported to be either harmful or protective. Herein, we review some key findings from clinical and animal model investigations, disc...

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Bibliographic Details
Main Authors: Ari Sudwarts, Gopal Thinakaran
Format: Article
Language:English
Published: BMC 2023-11-01
Series:Molecular Neurodegeneration
Online Access:https://doi.org/10.1186/s13024-023-00679-4