Imputation of ancient human genomes

Imputation of ancient human genomes

Abstract Due to postmortem DNA degradation and microbial colonization, most ancient genomes have low depth of coverage, hindering genotype calling. Genotype imputation can improve genotyping accuracy for low-coverage genomes. However, it is unknown how accurate ancient DNA imputation is and whether...

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Bibliographic Details
Main Authors: Bárbara Sousa da Mota, Simone Rubinacci, Diana Ivette Cruz Dávalos, Carlos Eduardo G. Amorim, Martin Sikora, Niels N. Johannsen, Marzena H. Szmyt, Piotr Włodarczak, Anita Szczepanek, Marcin M. Przybyła, Hannes Schroeder, Morten E. Allentoft, Eske Willerslev, Anna-Sapfo Malaspinas, Olivier Delaneau
Format: Article
Language:English
Published: Nature Portfolio 2023-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-39202-0

Internet

https://doi.org/10.1038/s41467-023-39202-0

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