A comprehensive multiomics approach reveals that high levels of sphingolipids in cardiac cachexia adipose tissue are associated with inflammatory and fibrotic changes

Abstract Cardiac cachexia is a deadly consequence of advanced heart failure that is characterised by the dysregulation of adipose tissue homeostasis. Once cachexia occurs with heart failure, it prevents the normal treatment of heart failure and increases the risk of death. Targeting adipose tissue i...

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Bibliographic Details
Main Authors: Yiwei Qu, Yong Wang, Tao Wu, Xue Liu, Huaizhe Wang, Dufang Ma
Format: Article
Language:English
Published: BMC 2023-12-01
Series:Lipids in Health and Disease
Subjects:
Online Access:https://doi.org/10.1186/s12944-023-01967-0