Area-specific alterations of synaptic plasticity in the 5XFAD mouse model of Alzheimer's disease: dissociation between somatosensory cortex and hippocampus.

Area-specific alterations of synaptic plasticity in the 5XFAD mouse model of Alzheimer's disease: dissociation between somatosensory cortex and hippocampus.

Transgenic mouse models of Alzheimer's disease (AD) that overproduce the amyloid beta peptide (Aβ) have highlighted impairments of hippocampal long-term synaptic plasticity associated with the progression of the disease. Here we examined whether the characteristics of one of the hallmarks of AD...

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Bibliographic Details
Main Authors: Nadine Crouzin, Kevin Baranger, Mélanie Cavalier, Yannick Marchalant, Catherine Cohen-Solal, François S Roman, Michel Khrestchatisky, Santiago Rivera, François Féron, Michel Vignes
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3775744?pdf=render

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http://europepmc.org/articles/PMC3775744?pdf=render

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