LIR Motif-Containing Hyperdisulfide β-Ginkgotide is Cytoprotective, Adaptogenic, and Scaffold-Ready

LIR Motif-Containing Hyperdisulfide β-Ginkgotide is Cytoprotective, Adaptogenic, and Scaffold-Ready

Grafting a bioactive peptide onto a disulfide-rich scaffold is a promising approach to improve its structure and metabolic stability. The ginkgo plant-derived β-ginkgotide β-gB1 is a highly unusual molecule: Small, hyperdisulfide, and found only in selected ancient plants. It also...

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Bibliographic Details
Main Authors: Bamaprasad Dutta, Jiayi Huang, Janet To, James P. Tam
Format: Article
Language:English
Published: MDPI AG 2019-06-01
Series:Molecules
Subjects:
adaptogenic
autophagy
β-ginkgotide
cytoprotective
cysteine-rich peptides
disulfide-rich scaffold
hyperdisulfide
hypoxia
LIR motif
ginkgo nuts
Online Access:https://www.mdpi.com/1420-3049/24/13/2417

Internet

https://www.mdpi.com/1420-3049/24/13/2417

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