Potential Cytoprotective and Regulatory Effects of Ergothioneine on Gene Expression of Proteins Involved in Erythroid Adaptation Mechanisms and Redox Pathways in K562 Cells

Potential Cytoprotective and Regulatory Effects of Ergothioneine on Gene Expression of Proteins Involved in Erythroid Adaptation Mechanisms and Redox Pathways in K562 Cells

This study aimed to establish the importance of ergothioneine (ERT) in the erythroid adaptation mechanisms by appraising the expression levels of redox-related genes associated with the PI3K/AKT/FoxO3 and Nrf2-ARE pathways using K562 cells induced to erythroid differentiation and H<sub>2</s...

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Bibliographic Details
Main Authors: Victoria Simões Bernardo, Flaviene Felix Torres, Carla Peres de Paula, João Pedro Maia de Oliveira da Silva, Eduardo Alves de Almeida, Anderson Ferreira da Cunha, Danilo Grünig Humberto da Silva
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Genes
Subjects:
antioxidants
therapeutic agent
redox adaptation
proteasome
Online Access:https://www.mdpi.com/2073-4425/13/12/2368

Internet

https://www.mdpi.com/2073-4425/13/12/2368

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