Identification of Key Determinants of Cerebral Malaria Development and Inhibition Pathways

Identification of Key Determinants of Cerebral Malaria Development and Inhibition Pathways

ABSTRACT Cerebral malaria (CM), coma caused by Plasmodium falciparum-infected red blood cells (iRBCs), is the deadliest complication of malaria. The mechanisms that lead to CM development are incompletely understood. Here we report on the identification of activation and inhibition pathways leading...

Full description

Bibliographic Details
Main Authors: Sung-Jae Cha, Xiang Yu, Brian D. Gregory, Yong Seok Lee, Tomoko Ishino, Robert O. Opoka, Chandy C. John, Marcelo Jacobs-Lorena
Format: Article
Language:English
Published: American Society for Microbiology 2022-02-01
Series:mBio
Subjects:
IGF1
biomarker
cerebral malaria
sporozoite
vascular injury
Online Access:https://journals.asm.org/doi/10.1128/mbio.03708-21

Internet

https://journals.asm.org/doi/10.1128/mbio.03708-21

Similar Items