Mechanisms of selective delivery of xanthophylls to retinal pigment epithelial cells by human lipoproteins

The xanthophylls, lutein and zeaxanthin, are dietary carotenoids that selectively accumulate in the macula of the eye providing protection against age-related macular degeneration. To reach the macula, carotenoids cross the retinal pigment epithelium (RPE). Xanthophylls and β-carotene mostly associa...

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Bibliographic Details
Main Authors: Sara E. Thomas, Earl H. Harrison
Format: Article
Language:English
Published: Elsevier 2016-10-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520353955