Single-cell transcriptome profiling reveals heterogeneous neutrophils with prognostic values in sepsis

Single-cell transcriptome profiling reveals heterogeneous neutrophils with prognostic values in sepsis

Summary: Neutrophils constitute the largest proportion of nucleated peripheral blood cells, and neutrophils have substantial heterogeneity. We profiled nearly 300,000 human peripheral blood cells in this study using single-cell RNA sequencing. A large proportion (>50%) of these cells were annotat...

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Bibliographic Details
Main Authors: Yucai Hong, Lin Chen, Jian Sun, Lifeng Xing, Yi Yang, Xiaohong Jin, Huabo Cai, Lianlian Dong, Liping Zhou, Zhongheng Zhang
Format: Article
Language:English
Published: Elsevier 2022-11-01
Series:iScience
Subjects:
Biological sciences
Immunology
Transcriptomics
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004222015735

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http://www.sciencedirect.com/science/article/pii/S2589004222015735

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