Acetyltransferase P300 Regulates Glucose Metabolic Reprogramming through Catalyzing Succinylation in Lung Cancer

Acetyltransferase P300 Regulates Glucose Metabolic Reprogramming through Catalyzing Succinylation in Lung Cancer

Aberrant protein post-translational modification is a hallmark of malignant tumors. Lysine succinylation (Ksucc) plays a vital role in cell energy metabolism in various cancers. However, whether succinylation can be catalyzed by acetyltransferase p300 remains unclear. In this study, we unveiled that...

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Bibliographic Details
Main Authors: Qingzhi Ma, Qingmei Zeng, Kun Wang, Meirui Qian, Jingzhuo Li, Hao Wang, Huijie Zhang, Jianli Jiang, Zhinan Chen, Wan Huang
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:International Journal of Molecular Sciences
Subjects:
<i>EP300</i>
lysine succinylation
<i>PGK1</i>
glucose metabolism
lung cancer
Online Access:https://www.mdpi.com/1422-0067/25/2/1057

Internet

https://www.mdpi.com/1422-0067/25/2/1057

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