ω-3 and ω-6 Polyunsaturated Fatty Acids Regulate the Proliferation, Invasion and Angiogenesis of Gastric Cancer Through COX/PGE Signaling Pathway

BackgroundThis study aims to investigate the effects of ω-3, ω-6 polyunsaturated fatty acids (PUFAs), and their middle metabolites prostaglandin (PGE)2 and PGE3 on proliferation, invasion, and angiogenesis formation of gastric cancer cells and to explore associated mechanism.MethodsRT-PCR and ELISA...

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Main Authors: Jiachi Ma, Chensong Zhang, Wanqing Liang, Lei Li, Jun Du, Chengwu Pan, Bangling Chen, Yuzhong Chen, Yuanpeng Wang
Format: Article
Jezik:English
Izdano: Frontiers Media S.A. 2022-02-01
Serija:Frontiers in Oncology
Teme:
Online dostop:https://www.frontiersin.org/articles/10.3389/fonc.2022.802009/full