Pharmacokinetics of single low dose primaquine in Ugandan and Congolese children with falciparum malariaResearch in context

Pharmacokinetics of single low dose primaquine in Ugandan and Congolese children with falciparum malariaResearch in context

Summary: Background: There are no pharmacokinetic data of single low dose primaquine (SLDPQ) as transmission blocking in African children with acute Plasmodium falciparum and glucose-6-phosphate dehydrogenase deficiency (G6PDd). Methods: Primaquine pharmacokinetics of age-dosed SLDPQ (shown previou...

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Main Authors: Mavuto Mukaka, Marie A. Onyamboko, Peter Olupot-Olupot, Pimnara Peerawaranun, Kanokon Suwannasin, Watcharee Pagornrat, Jindarat Kouhathong, Wanassanan Madmanee, Winifred Were, Cate Namayanja, Peter Onyas, Harriet Titin, Joy Baseke, Rita Muhindo, Daddy K. Kayembe, Pauline O. Ndjowo, Benjamin B. Basara, Georgette S. Bongo, Charles B. Okalebo, Grace Abongo, Sophie Uyoga, Thomas N. Williams, Chiraporn Taya, Mehul Dhorda, Arjen M. Dondorp, Naomi Waithira, Mallika Imwong, Kathryn Maitland, Caterina Fanello, Nicholas P.J. Day, Joel Tarning, Nicholas J. White, Walter R.J. Taylor
Format: Article
Language:English
Published: Elsevier 2023-10-01
Series:EBioMedicine
Subjects:
Primaquine
Transmission blocking
Age-based dosing
Plasmodium falciparum
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396423003717

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http://www.sciencedirect.com/science/article/pii/S2352396423003717

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