Expression, Purification and Characterization of Functional Teduglutide Using GST Fusion System in Prokaryotic Cells

Purpose: Teduglutide is the first and only FDA-approved drug for long-term treatment of short bowel syndrome (SBS). The current study aimed to present an approach for production of teduglutide using recombinant DNA technology. Methods: The coding gene for teduglutide was cloned into pGEX-2T vector,...

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Bibliographic Details
Main Authors: Ali Akbar Alizadeh, Saba Rasouli, Omid Jamshidi Kandjani, Salar Hemmati, Siavoush Dastmalchi
Format: Article
Language:English
Published: Tabriz University of Medical Sciences 2023-07-01
Series:Advanced Pharmaceutical Bulletin
Subjects:
Online Access:https://apb.tbzmed.ac.ir/PDF/apb-13-592.pdf