Epigenetic Regulation by Lysine Demethylase 5 (KDM5) Enzymes in Cancer

Epigenetic Regulation by Lysine Demethylase 5 (KDM5) Enzymes in Cancer

Similar to genetic alterations, epigenetic aberrations contribute significantly to tumor initiation and progression. In many cases, these changes are caused by activation or inactivation of the regulators that maintain epigenetic states. Here we review our current knowledge on the KDM5/JARID1 family...

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Bibliographic Details
Main Authors: Joyce Sayegh, Qin Yan, Lauren P. Blair, Jian Cao, Mike Ran Zou
Format: Article
Language:English
Published: MDPI AG 2011-03-01
Series:Cancers
Subjects:
KDM5
JARID1
RBP2
PLU1
SMCX
SMCY
LID
histone demethylase
cancer stem cell
drug resistance
Online Access:http://www.mdpi.com/2072-6694/3/1/1383/

Internet

http://www.mdpi.com/2072-6694/3/1/1383/

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