Antimicrobial Use, Human Gut Microbiota and Clostridium difficile Colonization and Infection
Clostridium difficile infection (CDI) is the most important cause of nosocomial diarrhea. Broad-spectrum antimicrobials have profound detrimental effects on the structure and diversity of the indigenous intestinal microbiota. These alterations often impair colonization resistance, allowing the estab...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2015-07-01
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Series: | Antibiotics |
Subjects: | |
Online Access: | http://www.mdpi.com/2079-6382/4/3/230 |