Antimicrobial Use, Human Gut Microbiota and Clostridium difficile Colonization and Infection

Clostridium difficile infection (CDI) is the most important cause of nosocomial diarrhea. Broad-spectrum antimicrobials have profound detrimental effects on the structure and diversity of the indigenous intestinal microbiota. These alterations often impair colonization resistance, allowing the estab...

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Bibliographic Details
Main Authors: Caroline Vincent, Amee R. Manges
Format: Article
Language:English
Published: MDPI AG 2015-07-01
Series:Antibiotics
Subjects:
Online Access:http://www.mdpi.com/2079-6382/4/3/230