In silico and in vitro evaluation of antiviral activity of wogonin against main protease of porcine epidemic diarrhea virus

In silico and in vitro evaluation of antiviral activity of wogonin against main protease of porcine epidemic diarrhea virus

The high mortality rate of weaned piglets infected with porcine epidemic diarrhea virus (PEDV) poses a serious threat to the pig industry worldwide, demanding urgent research efforts related to developing effective antiviral drugs to prevent and treat PEDV infection. Small molecules can possibly pre...

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Bibliographic Details
Main Authors: Jieru Wang, Xiaoyu Zeng, Dongdong Yin, Lei Yin, Xuehuai Shen, Fazhi Xu, Yin Dai, Xiaocheng Pan
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
porcine epidemic diarrhea virus (PEDV)
wogonin
main protease
antiviral activity
binding affinity
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2023.1123650/full

Internet

https://www.frontiersin.org/articles/10.3389/fcimb.2023.1123650/full

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