The relationship between P16 INK4A and TP53 promoter methylation and the risk and prognosis in patients with oesophageal cancer in Thailand

Abstract DNA methylation can regulate the expression of tumour suppressor genes P16 and TP53, environmental factors, which are both important factors related to an increased risk and prognosis of oesophageal cancer (EC). However, the association between these two genes methylation status, as well as...

Full description

Bibliographic Details
Main Authors: Arisara Poosari, Thitima Nutravong, Wises Namwat, Wiphawan Wasenang, Prakasit Sa-ngiamwibool, Piti Ungareewittaya
Format: Article
Language:English
Published: Nature Portfolio 2022-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-14658-0