B cell polygenic risk scores associate with anti-dsDNA antibodies and nephritis in systemic lupus erythematosus

B cell polygenic risk scores associate with anti-dsDNA antibodies and nephritis in systemic lupus erythematosus

Objective B cell function and autoantibodies are important in SLE pathogenesis. In this work, we aimed to investigate the impact of cumulative SLE B cell genetics on SLE subphenotype and autoantibody profile.Methods Female patients with SLE (n=1248) and healthy controls (n=400) were genotyped using...

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Bibliographic Details
Main Authors: Andreas Jönsen, Sarah Reid, Christopher Sjöwall, Solbritt Rantapää-Dahlqvist, Øyvind Molberg, Dag Leonard, Maija-Leena Eloranta, Johanna K Sandling, Martina Frodlund, Karin Bolin, Anders A Bengtsson, Karoline Lerang, Anna Rudin, Anna Hedenstedt, Ahmed Sayadi, Elisabeth Skoglund
Format: Article
Language:English
Published: BMJ Publishing Group 2023-10-01
Series:Lupus Science and Medicine
Online Access:https://lupus.bmj.com/content/10/2/e000926.full

Internet

https://lupus.bmj.com/content/10/2/e000926.full

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