Purification and initial characterization of Plasmodium falciparum K+ channels, PfKch1 and PfKch2 produced in Saccharomyces cerevisiae

Purification and initial characterization of Plasmodium falciparum K+ channels, PfKch1 and PfKch2 produced in Saccharomyces cerevisiae

Abstract Resistance towards known antimalarial drugs poses a significant problem, urging for novel drugs that target vital proteins in the malaria parasite Plasmodium falciparum. However, recombinant production of malaria proteins is notoriously difficult. To address this, we have investigated two p...

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Bibliographic Details
Main Authors: Karen Molbaek, Maria Tejada, Christina Hoeier Ricke, Peter Scharff-Poulsen, Peter Ellekvist, Claus Helix-Nielsen, Nirbhay Kumar, Dan A. Klaerke, Per Amstrup Pedersen
Format: Article
Language:English
Published: BMC 2020-09-01
Series:Microbial Cell Factories
Subjects:
Malaria
K-channels
Yeast
Recombinant protein
Online Access:http://link.springer.com/article/10.1186/s12934-020-01437-7

Internet

http://link.springer.com/article/10.1186/s12934-020-01437-7

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