Anemia in β-thalassemia patients targets hepatic hepcidin transcript levels independently of iron metabolism genes controlling hepcidin expression

Anemia in β-thalassemia patients targets hepatic hepcidin transcript levels independently of iron metabolism genes controlling hepcidin expression

Thalassemia associates anemia and iron overload, two opposite stimuli regulating hepcidin gene expression. We characterized hepatic hepcidin expression in 10 thalassemia major and 13 thalassemia intermedia patients. Hepcidin mRNA levels were decreased in the thalassemia intermedia group which presen...

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Bibliographic Details
Main Authors: Emilie Camberlein, Giuliana Zanninelli, Lénaïck Détivaud, Anna Rita Lizzi, Francesco Sorrentino, Stefania Vacquer, Marie-Bérengère Troadec, Emanuele Angelucci, Emmanuelle Abgueguen, Olivier Loréal, Paolo Cianciulli, Maria Eliana Lai, Pierre Brissot
Format: Article
Language:English
Published: Ferrata Storti Foundation 2008-01-01
Series:Haematologica
Online Access:https://haematologica.org/article/view/4693

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https://haematologica.org/article/view/4693

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