Streptococcus pneumoniae disrupts the structure of the golgi apparatus and subsequent epithelial cytokine response in an H2O2-dependent manner

Abstract Background Lung infections caused by Streptococcus pneumonia are a global leading cause of death. The reactive oxygen species H2O2 is one of the virulence factors of Streptococcus pneumoniae. The Golgi apparatus is essential for the inflammatory response of a eukaryotic cell. Golgi fragment...

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Bibliographic Details
Main Authors: Björn Klabunde, André Wesener, Wilhelm Bertrams, Stephan Ringshandl, Luke D. Halder, Evelyn Vollmeister, Bernd Schmeck, Birke J. Benedikter
Format: Article
Language:English
Published: BMC 2023-08-01
Series:Cell Communication and Signaling
Online Access:https://doi.org/10.1186/s12964-023-01233-x