Adenosine-Related Mechanisms in Non-Adenosine Receptor Drugs

Adenosine-Related Mechanisms in Non-Adenosine Receptor Drugs

Many ligands directly target adenosine receptors (ARs). Here we review the effects of noncanonical AR drugs on adenosinergic signaling. Non-AR mechanisms include raising adenosine levels by inhibiting adenosine transport (e.g., ticagrelor, ethanol, and cannabidiol), affecting intracellular metabolic...

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Bibliographic Details
Main Authors: Kenneth A. Jacobson, Marc L. Reitman
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Cells
Subjects:
adenosine receptor
nucleoside transport
CNS
inflammation
cardiovascular system
pain
Online Access:https://www.mdpi.com/2073-4409/9/4/956

Internet

https://www.mdpi.com/2073-4409/9/4/956

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