Investigation into length heteroplasmy in the mitochondrial DNA control region after treatment with bisulfite

We report on a method to analyze length heteroplasmy within the human mitochondrial genome in which there are polycytosine [poly(C)] stretches. These poly(C) tracts induce heteroplasmy with the resultant inherent problems of accurate sequence designations. In this study, 20 samples that exhibited le...

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Bibliographic Details
Main Authors: James Chun-I Lee, Li-Chin Tsai, Yu-Jen Yu, Chun-Yen Lin, Adrian Linacre, Hsing-Mei Hsieh
Format: Article
Language:English
Published: Elsevier 2016-04-01
Series:Journal of the Formosan Medical Association
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0929664615003575