Epitope Prediction Assays Combined with Validation Assays Strongly Narrows down Putative Cytotoxic T Lymphocyte Epitopes

Tumor vaccine design requires prediction and validation of immunogenic MHC class I epitopes expressed by target cells as well as MHC class II epitopes expressed by antigen-presenting cells essential for the induction of optimal immune responses. Epitope prediction methods are based on different algo...

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Bibliographic Details
Main Authors: Peng Peng Ip, Hans W. Nijman, Toos Daemen
Format: Article
Language:English
Published: MDPI AG 2015-03-01
Series:Vaccines
Subjects:
Online Access:http://www.mdpi.com/2076-393X/3/2/203