Estrogen Receptor β (ESR2) Transcriptome and Chromatin Binding in a Mantle Cell Lymphoma Tumor Model Reveal the Tumor-Suppressing Mechanisms of Estrogens

Estrogen Receptor β (ESR2) Transcriptome and Chromatin Binding in a Mantle Cell Lymphoma Tumor Model Reveal the Tumor-Suppressing Mechanisms of Estrogens

Mantle cell lymphoma (MCL) is a non-Hodgkin lymphoma with one of the highest male-to-female incidence ratios. The reason for this is not clear, but epidemiological as well as experimental data have suggested a role for estrogens, particularly acting through estrogen receptor β (ESR2). To study the E...

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Bibliographic Details
Main Authors: Dan Huang, Zhiqiang Huang, Rajitha Indukuri, Chandrashekar Bangalore Revanna, Mattias Berglund, Jiyu Guan, Konstantin Yakimchuk, Anastasios Damdimopoulos, Cecilia Williams, Sam Okret
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Cancers
Subjects:
mantle cell lymphoma
estrogens
estrogen receptor β
ESR2
xenograft
ibrutinib
Online Access:https://www.mdpi.com/2072-6694/14/13/3098

Internet

https://www.mdpi.com/2072-6694/14/13/3098

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