Chimeric rhinoviruses displaying MPER epitopes elicit anti-HIV neutralizing responses.

The development of an effective AIDS vaccine has been a formidable task, but remains a critical necessity. The well conserved membrane-proximal external region (MPER) of the HIV-1 gp41 glycoprotein is one of the crucial targets for AIDS vaccine development, as it has the necessary attribute of being...

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Bibliographic Details
Main Authors: Guohua Yi, Mauro Lapelosa, Rachel Bradley, Thomas M Mariano, Denise Elsasser Dietz, Scott Hughes, Terri Wrin, Chris Petropoulos, Emilio Gallicchio, Ronald M Levy, Eddy Arnold, Gail Ferstandig Arnold
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3765159?pdf=render