The iron-dopamine D1 coupling modulates neural signatures of working memory across adult lifespan

The iron-dopamine D1 coupling modulates neural signatures of working memory across adult lifespan

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Brain iron overload and decreased integrity of the dopaminergic system have been independently reported as brain substrates of cognitive decline in aging. Dopamine (DA), and iron are co-localized in high concentrations in the striatum and prefrontal cortex (PFC), but follow opposing age-related traj...

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Bibliographic Details
Main Authors: Jonatan Gustavsson, Jarkko Johansson, Farshad Falahati, Micael Andersson, Goran Papenberg, Bárbara Avelar-Pereira, Lars Bäckman, Grégoria Kalpouzos, Alireza Salami
Format: Article
Language:English
Published: Elsevier 2023-10-01
Series:NeuroImage
Subjects:
Dopamine
Iron
Working memory
Age
BOLD
Online Access:http://www.sciencedirect.com/science/article/pii/S1053811923004743

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http://www.sciencedirect.com/science/article/pii/S1053811923004743

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