The non-obese diabetic mouse strain as a model to study CD8+ T cell function in relapsing and progressive multiple sclerosis.

The non-obese diabetic mouse strain as a model to study CD8+ T cell function in relapsing and progressive multiple sclerosis.

Multiple sclerosis (MS) is a neurodegenerative disease resulting from an autoimmune attack on central nervous system myelin. While CD4+ T cell function in MS pathology has been extensively studied, there is also strong evidence that CD8+ T lymphocytes play a key role. Intriguingly, CD8+ T cells accu...

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Bibliographic Details
Main Authors: Prenitha Mercy eIgnatius Arokia Doss, Andrée-Pascale eRoy, AiLi eWang, Ana C Anderson, Manu eRangachari
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-10-01
Series:Frontiers in Immunology
Subjects:
Multiple Sclerosis
CD8+ T cell
Experimental autoimmune encephalomyelitis
CD4+ T cell
non-obese diabetic
relapsing-remitting multiple sclerosis
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00541/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00541/full

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