Structural‐Activity Relationship‐Inspired the Discovery of Saturated Fatty Acids as Novel Colistin Enhancers

Abstract The emergence and prevalence of mobile colistin resistance gene mcr have dramatically compromised the clinical efficacy of colistin, a cyclopeptide antibiotic considered to be the last option for treating different‐to‐treat infections. The combination strategy provides a productive and cost...

Full description

Bibliographic Details
Main Authors: Jinju Cai, Jingru Shi, Chen Chen, Mengping He, Zhiqiang Wang, Yuan Liu
Format: Article
Language:English
Published: Wiley 2023-10-01
Series:Advanced Science
Subjects:
Online Access:https://doi.org/10.1002/advs.202302182