Capture, unfolding, and detection of individual tRNA molecules using a nanopore device

Transfer RNAs (tRNA) are the most common RNA molecules in cells and have critical roles as both translators of the genetic code and regulators of protein synthesis. As such, numerous methods have focused on studying tRNA abundance and regulation, with the most widely used methods being RNA-seq and...

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Bibliographic Details
Main Authors: Andrew M Smith, Robin L AbuShumays, Mark eAkeson, David L Bernick
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-06-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fbioe.2015.00091/full