Extracellular Vesicle–associated GARP/TGFβ:LAP Mediates “Infectious” Allo-tolerance

Background. Here we test the hypothesis that, like CD81-associated “latent” IL35, the transforming growth factor (TGF)β:latency-associated peptide (LAP)/glycoprotein A repetitions predominant (GARP) complex was also tethered to small extracellular vesicles (sEVs), aka exosomes, produced by lymphocyt...

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Bibliographic Details
Main Authors: William J. Burlingham, PhD, Ewa Jankowska-Gan, MS, John H. Fechner, MS, Christopher J. Little, MD, Jianxin Wang, PhD, Seungpyo Hong, PhD, Miraf Molla, BS, Jeremy A. Sullivan, PhD, David P. Foley, MD
Format: Article
Language:English
Published: Wolters Kluwer 2023-06-01
Series:Transplantation Direct
Online Access:http://journals.lww.com/transplantationdirect/fulltext/10.1097/TXD.0000000000001475