N-acetylcysteine Amide AD4/NACA and Thioredoxin Mimetic Peptides Inhibit Platelet Aggregation and Protect against Oxidative Stress

N-acetylcysteine Amide AD4/NACA and Thioredoxin Mimetic Peptides Inhibit Platelet Aggregation and Protect against Oxidative Stress

In the present study, we tested the effect of small-molecular-weight redox molecules on collagen-induced platelet aggregation. We used N-acetylcysteine amide (AD4/NACA), the amide form of N-acetylcysteine (NAC), a thiol antioxidant with improved lipophilicity and bioavailability compared to NAC, and...

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Bibliographic Details
Main Authors: Sonia Eligini, Marco Munno, Daphne Atlas, Cristina Banfi
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:Antioxidants
Subjects:
platelet
aggregation
N-acetylcysteine
N-acetylcysteine amide
thioredoxin-mimetic peptides
clotting time
Online Access:https://www.mdpi.com/2076-3921/12/7/1395

Internet

https://www.mdpi.com/2076-3921/12/7/1395

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