Elucidating the Host Interactome of EV-A71 2C Reveals Viral Dependency Factors

Viral protein 2C plays a critical role in EV-A71 replication. The discovery of 2C binding proteins will likely provide potential targets to treat EV-A71 infection. Here, we provide a global proteomic analysis of the human proteins that interact with the EV-A71 2C protein. TRIM4, exportin2, and ARFGA...

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Bibliographic Details
Main Authors: Ye Li, Xia Jian, Peiqi Yin, Guofeng Zhu, Leiliang Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-04-01
Series:Frontiers in Microbiology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2019.00636/full