Deletion of CD36 exhibits limited impact on normal hematopoiesis and the leukemia microenvironment
Abstract Background CD36 has been identified as a potential therapeutic target both in leukemic cells and in the tumor immune microenvironment. In acute myeloid leukemia (AML), we found that APOC2 acts with CD36 to promote leukemia growth by activating the LYN-ERK signaling. CD36 also plays a role i...
Main Authors: | , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2023-05-01
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Series: | Cellular & Molecular Biology Letters |
Subjects: | |
Online Access: | https://doi.org/10.1186/s11658-023-00455-8 |